Imagine a fork-tender, juicy beef roast infused with tangy pepperoncini and rich, savory flavors—all ready in just over 2 hours! This Mississippi Pot Roast Instant Pot recipe is a game-changer for busy weeknights, meal prepping, or a comforting family dinner. If you’re looking for a no-fail, flavorful pot roast with minimal effort, this is it!

Ingredients and Preparation Steps
Here’s everything you need to make this mouthwatering Instant Pot Mississippi Pot Roast at home.
Ingredients

- 1 (14 oz) can beef broth
- 3 ½ lbs beef chuck roast, cut into 3 or 4 chunks
- 3 tbsp olive oil
- ½ (16 oz) jar pepperoncini peppers with juice
- 1 (1 oz) package ranch dressing mix
- 1 (1 oz) package dry onion soup mix
Step 1: Sear the Beef

First, set your Instant Pot to sauté mode and heat the olive oil. Once hot, add the beef chunks and sear for 2–3 minutes on each side until nicely browned. This step locks in flavor and gives the roast a delicious crust.
Step 2: Add Seasonings and Broth

Next, pour in the beef broth, ensuring the beef is partially submerged. Sprinkle the ranch dressing mix and dry onion soup mix evenly over the meat.
Step 3: Add the Pepperoncini

Now, add the pepperoncini peppers along with half of the jar’s juice. This ingredient gives the roast its signature tangy kick and helps tenderize the meat.
Step 4: Pressure Cook to Perfection
Close the Instant Pot lid and set it to high pressure for 110 minutes. Once the timer is up, let the pressure release naturally for 10–40 minutes—this ensures maximum tenderness.
Step 5: Shred and Serve

Finally, use two forks to shred the beef directly in the Instant Pot. Stir everything together so the meat absorbs all the flavorful juices. Serve over mashed potatoes, rice, or in a sandwich!
When to Enjoy This Savory Mississippi Pot Roast
The best part about this Instant Pot Mississippi Pot Roast is how versatile it is! Here are some of the best ways to enjoy it:
- Sunday Dinners: A hearty meal the whole family will love.
- Meal Prep: Make a big batch and enjoy leftovers throughout the week.
- Game Day Sandwiches: Serve on hoagie rolls with melted cheese for a crowd-pleaser.
- Comfort Food Nights: Perfect for cozy evenings with a side of mashed potatoes.
Looking for more comforting dishes? Try our Beef Pot Pie or Smoked Mac and Cheese to complete your meal!
Frequently Asked Questions About Mississippi Pot Roast Instant Pot
Can I use a different cut of beef?
Yes! While chuck roast is ideal for its marbling and tenderness, you can also use brisket or bottom round roast.
Do I have to use pepperoncini peppers?
Pepperoncini add tang and tenderness, but if you prefer a milder taste, you can substitute banana peppers or omit them entirely.
How do I make the roast less salty?
To reduce saltiness, use a low-sodium beef broth and opt for homemade seasoning blends instead of pre-packaged ones.
Can I make this in a slow cooker?
Absolutely! Follow the same steps but cook on low for 8 hours or high for 4–5 hours.
What can I serve with Mississippi Pot Roast?
This dish pairs beautifully with mashed potatoes, rice, roasted vegetables, or crusty bread to soak up the delicious gravy.
For more detailed step-by-step guides, check out this Instant Pot Mississippi Roast recipe on AllRecipes!
Pro Tips for Perfect Mississippi Pot Roast Instant Pot
To make sure your pot roast turns out juicy and full of flavor every time, follow these expert tips:
- Choose the Right Cut: Use a well-marbled chuck roast for the most tender and flavorful results.
- Don’t Skip Searing: Searing the beef before pressure cooking locks in rich, deep flavors.
- Adjust the Spice Level: Add extra pepperoncini for more heat or remove seeds for a milder taste.
- Thicken the Gravy: If you prefer a thicker sauce, remove the beef after cooking and stir in a cornstarch slurry (1 tbsp cornstarch + 2 tbsp water) into the juices.
- Natural Pressure Release is Key: Let the Instant Pot release pressure naturally for at least 10 minutes to ensure maximum tenderness.
- Enhance the Flavor: Add sliced onions, carrots, or garlic before cooking for a richer sauce.
- Make it a One-Pot Meal: Toss in baby potatoes or cauliflower during the last 30 minutes of cooking.
Storage and Reheating Tips
Leftovers? No problem! This Mississippi Pot Roast tastes even better the next day. Here’s how to store and reheat it properly:
- Refrigeration: Store leftovers in an airtight container with juices for up to 4 days.
- Freezing: Freeze shredded roast with its juices in a freezer-safe bag for up to 3 months.
- Reheating on the Stovetop: Heat in a saucepan over low heat with a splash of beef broth to keep it moist.
- Reheating in the Microwave: Cover and heat in 30-second intervals, stirring between each, until warmed through.
- Reheating in the Instant Pot: Use the “Sauté” mode for 5–10 minutes, stirring occasionally.
Perfect Pairings for Mississippi Pot Roast Instant Pot
Want to make this meal even better? Here are some amazing sides and accompaniments:
- Classic Mashed Potatoes: Creamy mashed potatoes soak up the rich, savory gravy.
- Smoked Mac and Cheese: Try this Smoked Mac and Cheese for a bold, cheesy side.
- Roasted Vegetables: Carrots, Brussels sprouts, or green beans add a fresh balance to the dish.
- Crusty Bread: A warm baguette or dinner rolls are perfect for dipping into the flavorful juices.
- Beef Pot Pie: Turn your leftovers into a delicious Beef Pot Pie for a second meal.
There’s nothing quite like a comforting, flavorful meal that practically cooks itself. This Mississippi Pot Roast Instant Pot recipe is a must-try for anyone who loves tender, juicy beef with bold flavors. Whether you’re serving it over mashed potatoes, stuffing it into a sandwich, or using leftovers for a creative new dish, this recipe never disappoints!
Have you tried this recipe? Let us know in the comments below how you served it! Do you have any special twists or secret ingredients? We’d love to hear your take.
For more easy and delicious recipes, check out our collection of comfort food favorites:
- Smoked Mac and Cheese – The ultimate cheesy side dish.
- Beef Pot Pie – A cozy and flaky classic.
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Happy cooking!
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Mississippi Pot Roast Instant Pot Recipe
- Total Time: 2 hrs
- Yield: 10
Description
Get ready for the most tender, flavor-packed beef roast you’ll ever make! This Instant Pot recipe delivers juicy, fall-apart beef with tangy pepperoncini and a rich, savory sauce—all in just over 2 hours. Perfect for meal prep, sandwiches, or serving over mashed potatoes!
Ingredients
– 1 (14 oz) can beef broth
– 3 ½ lbs beef chuck roast, cut into 3 or 4 chunks
– 3 tbsp olive oil
– ½ (16 oz) jar pepperoncini peppers with juice
– 1 (1 oz) package ranch dressing mix
– 1 (1 oz) package dry onion soup mix
Instructions
1. First, set your Instant Pot to sauté mode and heat the olive oil. Sear the beef chunks for 2-3 minutes on each side until browned.
2. Next, pour in the beef broth, then sprinkle the ranch dressing mix and onion soup mix over the beef. Add the pepperoncini and juice.
3. After that, close the lid, set to high pressure, and cook for 110 minutes. Let the pressure release naturally for about 10-40 minutes.
4. Finally, shred the beef using two forks, mix it with the flavorful juices, and serve!
Notes
For extra depth of flavor, add sliced onions and carrots before pressure cooking. They’ll melt into the sauce, making it even more delicious!
- Prep Time: 5 mins
- Cook Time: 1 hr 50 mins
- Category: Comfort Food
Nutrition
- Calories: 343
- Fat: 27g
- Carbohydrates: 4g
- Protein: 19g